Gene Expression Profiling for Phosphorylation ResearchINQUIRY
Creative BioMart provides comprehensive gene expression profiling services for kinase/phosphatase biology research and pharmaceutical development. Our expertise coupled with state-of-the-art techniques enables us to offer you one-stop services and customized solutions to accelerate your project success.
Gene expression profiling refers to the measurement of the activity of thousands of genes even the entire genome at once in cells at any given moment. It provides a high-throughput approach and accurate information for gene expression to create a global picture of cellular function. Microarray and sequencing are two commonly used techniques. Gene expression profiling has been widely used in basic scientific research, pathological research and drug development. It can also be used as a diagnostic tool.
Genes encoding kinases and phosphatases are key regulators of multiple cellular processes. Many kinases and phosphatases are known to be a cause of major diseases, such as cancer, diabetes and chronic inflammatory diseases. Many efforts have been devoted to the study of kinase/phosphatase gene expression profiles in diseases. Kinases and phosphatases hold promise as potential therapeutic targets for diverse diseases and are of great importance for the pharmaceutical industry.
Figure 1. Overview of pan-KI transcriptomic profiling in human primary cardiomyocyte-like cells. (van Hasselt J G C, et al., 2020)
Equipped with advanced platforms such as NGS sequencing, microarrays, and bioinformatics, we provide comprehensive services to fully meet our customers' requirements. Our available services include, but are not limited to the following:
|Microarray-Based Gene Expression Profiling
|Analysis of thousands of genes expressed in a particular cell at a given time.
Discovery of biomarkers and appropriate targets for therapeutic applications.
|Sequencing-Based Gene Expression Profiling
|Identification of novel transcripts, alternative splicing, and gene fusion events.
Wide applicability and broad dynamic range.
|PCR-Based Gene Expression Profiling
|Quantitative analysis of gene expression applicable to basic molecular biology, medicine, and diagnostics.
Sequence-specificity and remarkable sensitivity.
|High-throughput Gene Expression Profiling
|One of the most important and powerful methods in biomedical research.
Utilized in achieving the goal of multidimensional integration of physiology.
|Single-Cell Gene Expression Profiling
|Visualization of gene expression inside single cells with high spatial-temporal resolution.
Accurately description of gene expression differences in individual cells from the same tissue.
|In Vivo Gene Expression Profiling
|Rapidly and directly monitor in vivo gene expression.
A key step towards rapid progress in disease prevention, detection, diagnosis and treatment.
|Validation of Gene Expression Profiles
|Diverse methods for validating gene expression profiles to ensure the reliability and validity.
Custom Project Workflow
Features and Benefits
- Quality assurance – Strict quality control to ensure high-quality and high accuracy.
- Expertise – A professional team of molecular biologists with extensive experience.
- Flexibility – Tailored solutions for specific needs.
- Fast turnaround time – Efficient services with guaranteed turnaround time.
- Economical pricing – Discounts available and no hidden charges.
Creative BioMart has always been committed to providing customers with high-quality products and services. Our innovative techniques coupled with our large collection of products allow us to tackle your project to save your time and effort. Simply provide us your project details and exact specifications, our scientific team will do the rest and provide satisfactory results.
Please do not hesitate to contact us if you need any further information. We sincerely look forward to further cooperation.
- van Hasselt J G C, et al. Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity. Nature communications, 2020, 11(1): 1-12.
- Jin J H, et al. Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans. Nature communications, 2020, 11(1): 1-17.