Virus Packaging Services for Phosphorylation Research

Virus Packaging Services for Phosphorylation Research

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Virus Packaging Services for Phosphorylation Research

INQUIRY

Creative BioMart provides high-quality and express virus packaging services for kinase/phosphatase biology research and pharmaceutical development. We offer flexible services ranging from vector design to virus titration. Downstream research services are also available upon request.

Brief Introduction

Viruses are made up of nucleic acid genomes and a protective protein shell called capsid. Genome packaging is a fundamental process in a viral life cycle. Viruses have evolved specialized molecular mechanisms to efficiently transport their genomes inside the infected cells. Viral vectors have become powerful tools used by molecular biologists to efficiently deliver genetic materials into cells in vitro or into living organisms in vivo while protecting genes from degradation during the delivery process. Moreover, viruses are ideal tools to deliver genetic information to hard-to-transfect cells and to specific cells in an organism. Viral vectors have key properties of safety, low toxicity, stability, cell-type specificity, and easy identification, expanding their applications from basic research to gene therapy, vaccine development, and drug delivery.

In kinase/phosphatase biology, viral vectors can be used to study the function of the specific kinases and phosphatase by expressing protein-coding genes. Viral delivery systems can also be adapted to or paired with genome editing technologies for functional studies. Moreover, viral gene therapy targeting kinases/phosphatase holds promise for the treatment of multiple diseases. On the other hand, both viral and cellular kinases/phosphatases play an important role in biochemical events during virus infection. Profiling of kinases/phosphatases is also important for virus research and drug development for infectious diseases.

Virion-packaged pkm2 affects reverse transcription efficiency of hiv1 by blocking virion recruitment of trnalys3. 

Figure 1. Virion-packaged pkm2 affects reverse transcription efficiency of hiv1 by blocking virion recruitment of trnalys3. (Mouree K R, et al., 2018)

General Virus Packaging Workflow

General Virus Packaging Workflow

Available Services

Creative BioMart offers comprehensive virus packaging service options to best meet your research needs. We offer customers the advantages of high-quality vectors, ready-to-transfect particles, high-titer virus, and a reasonable turnaround time.

Types of Virus

  • Lentivirus
  • Adenovirus
  • Baculovirus
  • Measles virus
  • Rabies virus
  • Plant virus
  • Hybrid virus
  • Retrovirus
  • Adeno-associated virus
  • Herpes simplex virus
  • Pseudovirus
  • Vesicular stomatitis virus
  • Oncolytic virus
  • Virus-like particles

Service Options

  • Virus design
  • Virus packaging
  • Virus titration
  • Genome editing
  • Structure determination
  • Viral delivery systems
  • GMP-grade services
  • Vector construction
  • Virus production
  • Virus purification
  • Virus engineering
  • Protein production
  • Cell engineering
  • QC testing

Custom Project Workflow

Custom Project Workflow

Features and Benefits

  • Quality assurance – Strict quality control to ensure high-quality and high-purity.
  • Expertise – A professional team of molecular biologists with extensive experience.
  • Strong versatility – Different choices of virus types coupled with comprehensive services for different purposes and applications.
  • Fast turnaround time – Efficient services with guaranteed turnaround time.
  • Economical pricing – Discounts available and no hidden charges.

Creative BioMart has always been committed to providing customers with high-quality products and services. Our innovative techniques coupled with our large collection of related products allow us to tackle your project to save your time and effort. Simply provide us your project details and exact specifications, our scientific team will do the rest and provide satisfactory results.

If you need any further information or have any specific requirements, please do not hesitate to contact us. We sincerely look forward to further cooperation.

References

  • Mouree K R, et al. Virion-Packaged Pyruvate Kinase Muscle Type 2 Affects Reverse Transcription Efficiency of Human Immunodeficiency Virus Type 1 by Blocking Virion Recruitment of tRNALys3. Biological and Pharmaceutical Bulletin, 2018, 41(4): 612-618.
  • Wang Y, et al. shRNA knockdown of integrin‐linked kinase on hPDLCs migration, proliferation, and apoptosis under cyclic tensile stress. Oral Diseases, 2020, 26(8): 1747-1754.
For research use only. Not intended for any clinical use.